Cold Spring Harbor Laboratory receives new fu

image: The bioRxiv and medRxiv preprint servers have changed the way researchers communicate. The online research archives created by CSHL and its partners have become invaluable resources for the global scientific community. A new injection of funding from the Chan Zuckerberg Initiative will help support the platforms’ growth and improve their feedback processes.
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Credit: Chan Zuckerberg Institute, bioRxiv and medRxiv

COLD SPRING HARBOUR, NY — Cold Spring Harbor Laboratory (CSHL) today announced that preprint servers bioRxiv and medRxiv received renewed funding from the Chan Zuckerberg Initiative (CZI). CZI has supported bioRxiv since 2017 and medRxiv since 2020. The latest grants, totaling $6.1 million, will support the expansion of server operations through 2024 and a partnership with the annotation platform Hypothesis to improve commenting and feedback processes on preprints.

With the encouragement and financial support of CZI, bioRxiv (pronounced “bio archive”) and medRxiv (“med archive”) have quickly become central information resources, transforming the way scientists communicate worldwide. The servers offer researchers a free platform to share and compare their work. Manuscripts are selected but not peer reviewed. Authors publish them when they choose, not following submission to a journal, and update them as needed. Preprints attract attention, comments and citations, and enable early collaboration among scientists. Each year, bioRxiv and medRxiv host the discoveries of tens of thousands of scientists and share them with tens of millions of readers.

These free and open servers have proven to be invaluable public health tools throughout the COVID-19 pandemic. Of the 206,000 preprints on the servers, more than 25,000 have been published since 2020 that have helped scientists understand the biology of the coronavirus and streamline the development of safe and effective vaccines and treatment options.

John Inglis, co-founder of bioRxiv and medRxiv, said, “Our preprint team is extremely encouraged by CZI’s commitment to continue supporting our work and our vision for the future. We anticipate continued growth and greater diversity of authors and content, while engaging more scientists in the conversations taking place on and beyond these fast and open communication platforms. Preprints in biomedicine have reinvented research communication, and we look forward to working with partners, including institutions and other funding bodies, interested in joining CZI and CSHL to realize this bold ambition.

“The bioRxiv and medRxiv servers have transformed the way biomedical science is shared and the way researchers collaborate,” said Steve Quake, chief scientific officer of CZI. “We are delighted to extend our support to these platforms and hope that other institutions will join in efforts to further develop these essential resources.”

“The promise of an open, interoperable conversation layer for commenting, reviewing, community and more on literature runs deep,” said Dan Whaley, Founder/CEO of “We are thrilled to have the opportunity to work closely with the bioRxiv team to meet the needs of their community.”

This announcement comes at the right time on National STEM Day, a day dedicated to science, technology, engineering and math education. Since CSHL launched bioRxiv in 2013, preprint servers have emerged in other STEM-related fields, all sharing the common goal of advancing human knowledge through a free and open exchange of research findings.

The medRxiv server is co-managed by Cold Spring Harbor Laboratory, Yale University, and global knowledge provider BMJ. Harlan Krumholz, professor of medicine at Yale University, co-founder of medRxiv and leader of the Yale Open Data Access (YODA) project, said, “medRxiv has transformed clinical research, and yet it has only just begun. The goal is to engage all scientists in early and frequent data sharing so they can foster collaboration, elicit constructive feedback, and accelerate science to improve patient outcomes.

About the Cold Spring Harbor Laboratory: Founded in 1890, Cold Spring Harbor Laboratory has shaped contemporary biomedical research and education with programs in cancer, neuroscience, plant biology, and quantitative biology. Home to eight Nobel laureates, the private non-profit laboratory employs 1,000 people including 600 scientists, students and technicians. For more information, visit

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